Fat emulsion infusion aluminum foil2/26/2024 ![]() ![]() Lipid administration may also affect the heart in a metabolically advantageous way by improving fatty acid transport (Weinberg 2006). High lipid partition constant and large volumes of distribution are good predictors of success when using lipid therapy (French 2011). In toxicity secondary to highly lipid soluble substances, exogenous lipids provide an alternative source of binding (Rowlingson 2008), commonly known as the "lipid sink" effect. Nutrilipid: 20% (250 mL, 500 mL, 1000 mL) Pharmacology Mechanism of Actionįat emulsion is metabolized and utilized as an energy source provides the essential fatty acids, linoleic acid, and alpha linolenic acid necessary for normal structure and function of cell membranes in local anesthetic toxicity, lipid emulsion probably extracts lipophilic local anesthesia from cardiac muscle ![]() Excipient information presented when available (limited, particularly for generics) consult specific product labeling.Ĭlinolipid: 20% (100 mL, 250 mL, 500 mL, 1000 mL)
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